Experience the REM-I Platform

platform

Introducing the REM-I Platform

Methodologies to assess and characterize cell morphology, which can be highly indicative of phenotype and function, have been limited to either imaging or sorting with labels, until now.

The REM-I Platform takes the best of these worlds to provide imaging of single cells and label-free sorting in one platform leveraging AI.

True imaging

High-resolution imaging of single cells

The REM-I instrument takes high-speed, high-resolution brightfield images of single cells to capture information about morphology.

Gentle sorting

6-way, label-free sorting

A label-free workflow and gentle microfluidics means the cells you sort are minimally perturbed and viable for downstream analysis.

High-dimensional output

Powered by Deepcell’s Human Foundation Model

The Human Foundation Model assesses many dimensions of cell morphology for a high-dimensional characterization of each cell.

Powerful data suite

Real-time analysis of single cell morphology

Store, visualize, and analyze single cell image and high-dimensional cell morphology data with the Axon data suite.

A single, streamlined workflow
STEP 01/04
Prepare cells into single cell suspension
STEP 02/04
Image single cells in flow
STEP 03/04
Characterize cells in real-time with the HFM
STEP 04/04
Analyze data and optionally collect cell populations of interest for further analysis

Applications

Explore drivers of disease state, drug effects, developmental processes, perturbations, and more using high-dimensional morphology as its own modality.
01

Cancer research

Detect disease and identify morphological heterogeneity within and between cancer samples

02

Developmental biology

Classify cells by type and activation state with morphology as a marker

03

Cell & gene therapy

Predict the effect of genetic perturbations on phenotype with morphology

04

Drug & functional screening

Screen for cell health and morphological impacts of drug treatments

Dr. Peter van der Spek

Professor of Clinical Bioinformatics, Pathology
“The biggest advantage is that we don’t have to do staining – we simply push our cells/samples through REM-I and by the end of the day you have the high-dimensional morphology data of 100,000 or more cells.”
Dr. Peter van der Spek - Professor of Clinical Bioinformatics, Pathology

Dr. Andrew Filby

Professor, Flow Cytometry Core Director, Newcastle University
“There are different methods for characterizing cells at the single cell level, for example flow cytometry or imaging cells in flow, but they perturb the cells and don’t have the ability to sort for downstream analysis like REM-I does.”
Dr. Andrew Filby - Professor, Flow Cytometry Core Director, Newcastle University

Dr. Andy Tsai

Postdoctoral Scholar, Neurology, Stanford University
“We’ve seen first hand how the REM-I platform can validate and speed up the discovery and diagnosis of disease.”
Dr. Andy Tsai - Postdoctoral Scholar, Neurology, Stanford University

Dr. Jennifer Yokoyama

Associate Professor, Neurology, USCF Weill Institute for Neurosciences
“Mopholomics represents the natural next step to learn more about diseases, their biology, and identify novel targets for disease treatment in an unbiased fashion.”
Dr. Jennifer Yokoyama - Associate Professor, Neurology, USCF Weill Institute for Neurosciences